Pictet–Spengler condensations using 4-(2-aminoethyl)coumarins

Abstract

Amino-substituted coumarins undergo Pictet–Spengler condensations with 3-ketosteroids to afford spirocyclic androgens for the study 17-oxidoreductases for intracrine, androgen metabolism.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2020
Source ID
10.1039/d0nj02664f

Entities

People

  • Alexander H. Williams
  • Andrii G. Balia
  • Chang-Guo Zhan
  • Chunming Liu
  • David S Watt
  • James L Mohler
  • Kristin L. Begley
  • Liliia M. Kril
  • Michael V Fiandalo
  • Przemyslaw Wyrebek
  • Sean R Parkin
  • Vitaliy M Sviripa
  • Vivekanandan Subramanian
  • Xi Chen

Organizations

  • American Cancer Society
  • National Institutes of Health
  • National Science Foundation
  • Roswell Park Comprehensive Cancer Center
  • South Central Minzu University
  • United States Army
  • United States Department of Defense
  • University of Kentucky
  • Yusuf Hamied Department of Chemistry

Tags

Fields of Study

  • Chemistry