An electrochemical biosensor exploiting binding-induced changes in electron transfer of electrode-attached DNA origami to detect hundred nanometer-scale targets

Abstract

Using DNA origami as the recognition element in an electrochemical biosensor enables the selective and direct detection of “mesoscale” virus-sized analytes.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2020
Source ID
10.1039/d0nr00952k

Entities

People

  • Alexander K. Ng
  • Carlos E Castro
  • Chao-min Huang
  • Hai-Jun Su
  • Kevin W Plaxco
  • Muaz Sadeia
  • Natalie Williams
  • Nathan Ogden
  • Netzahualcóyotl Arroyo-Currás
  • Philip S. Lukeman
  • Roberto C Andresen Eguiluz
  • Tammy Afif
  • Yekaterina Fyodorova

Organizations

  • Army Research Office
  • Johns Hopkins School of Medicine
  • Ohio State University
  • Queens College
  • St. John's University
  • United States Army
  • University of California, Santa Barbara
  • Yusuf Hamied Department of Chemistry

Tags

Fields of Study

  • Chemistry

Readers

  • Electrochemical Surface Science
  • Nanocomposite Materials Science

Technology Areas

  • Biotechnology
  • Microelectronics
  • Microelectronics - Microelectromechanical Systems