Ultrasensitive small molecule fluorogenic probe for human heparanase
Abstract
Heparanase, a critical enzyme involved in the remodeling of the extracellular matrix, activates a disaccharide probe HADP to give a strong fluorescence signal.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2021
- Source ID
- 10.1039/d0sc04872k
Entities
People
- Arjun Kafle
- Benjamin Fetrow
- Changjian Xie
- Chao Cui
- Chenglong Li
- Gustavo Seabra
- Hua Guo
- Jian Liu
- Jun Liu
- Kelton A. Schleyer
- Kunlun Yin
- Lina Cui
- Paul K. P. Henderson
- Peter Z. Fatland
- Tyrel L. Bryan
- Ying Wang
- Yongmei Xu
Organizations
- National Institute of General Medical Sciences
- National Institutes of Health
- United States Department of Defense
- University of Florida
- University of New Mexico
- University of North Carolina