Simulating drug concentrations in PDMS microfluidic organ chips

Abstract

A simulation method for predicting drug responses is described that overcomes challenges relating to absorption of hydrophobic drug molecules by Organ Chips made from polydimethylsiloxane (PDMS).

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2021
Source ID
10.1039/d1lc00348h

Entities

People

  • Alican Ozkan
  • Crystal Oh
  • Donald E. Ingber
  • Gautam Mahajan
  • Jennifer Grant
  • Rachelle Prantil-baun

Organizations

  • Defense Advanced Research Projects Agency
  • Harvard Medical School
  • Harvard University
  • National Center for Advancing Translational Sciences

Tags

Fields of Study

  • Chemistry

Readers

  • Computational Modeling and Simulation
  • Nanoscale Plasmonic Nanotechnology
  • Toxicology/Environmental Toxicology