Cortical spheroids display oscillatory network dynamics
Abstract
3-D spheroid cultures contain networks that develop by 9 days and develop increasingly complex network activity patterns as they mature. We demonstrate, for the first time, that spheroids exhibit network activity similar to in vivo network events.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2021
- Source ID
- 10.1039/d1lc00737h
Entities
People
- Brian Theyel
- Diane Hoffman-Kim
- Jessica Sevetson
Organizations
- Brown University
- National Institute of Environmental Health Sciences
- Office of Naval Research