Small molecule peptidomimetic trypsin inhibitors: validation of an EKO binding mode, but with a twist
Abstract
A commonality noticed between structures of trypsin and natural trypsin inhibitors leads to a new small molecule inhibitor design strategy.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2022
- Source ID
- 10.1039/d1ob02127c
Entities
People
- Arthur Laganowsky
- Charles Packianathan
- Kevin Burgess
- Rui-Liang Lyu
- Shaon Joy
Organizations
- Cancer Prevention and Research Institute of Texas
- National Institutes of Health
- National Science Foundation
- Robert A. Welch Foundation
- Texas A&M University
- United States Department of Defense