The quantum dot vs. organic dye conundrum for ratiometric FRET-based biosensors: which one would you chose?

Abstract

We report a combined experimental and computational study to systematically compare the nature of the dye, i.e., organic fluorophore vs. inorganic nanoparticle, and the position of the FRET donor or acceptor on the biosensor performances.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2022
Source ID
10.1039/d1sc06921g

Entities

People

  • Allison M Dennis
  • Andy Fan
  • Catherine M. Klapperich
  • Chloé Grazon
  • James Galagan
  • Margaret Chern
  • Mark W Grinstaff
  • Patrick Lally
  • R Baer
  • Sébastien Lecommandoux

Organizations

  • Boston University
  • Defense Advanced Research Projects Agency
  • Horizon 2020
  • National Institutes of Health
  • Office of Naval Research
  • Uniformed Services University of the Health Sciences

Tags

Readers

  • Chemistry (specifically Chemical Fluorescence)
  • Computational Modeling and Simulation
  • Nanoscale Plasmonic Nanotechnology

Technology Areas

  • Biotechnology
  • Quantum Computing