An automated system for interrogating the evolution of microbial endosymbiosis
Abstract
Using an automated microfluidic SEER platform, we rapidly evolved laboratory naïve E. coli strain DH5α to possess enhanced capability to survive within host cells, and identified the critical role of gene CpxR in such microbial endosymbiosis.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2023
- Source ID
- 10.1039/d2lc00602b
Entities
People
- Alice R. Wattam
- Allan W. Dickerman
- Arum Han
- Can Huang
- Clark Cucinell
- Fengguang Guo
- Han Wang
- James Dalton, Iii
- Jasmine Olivares
- Olga Belyanina
- Paul de Figueiredo
- Qing-Ming Qin
Organizations
- Gates Foundation
- Texas A&M Health Science Center
- Texas A&M University
- Tsinghua University
- United States Army Research Laboratory
- University of Virginia