Interplay between substrate rigidity and tissue fluidity regulates cell monolayer spreading
Abstract
Using a cell-based computational model of a spreading cell monolayer, we show that the interplay between tissue fluidity and substrate rigidity regulates the rate of collective spreading.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2022
- Source ID
- 10.1039/d2sm00757f
Entities
People
- Michael F. Staddon
- Michael Murrell
- Shiladitya Banerjee
Organizations
- Army Research Office
- Carnegie Mellon University
- Center for Systems Biology Dresden
- Human Frontier Science Program
- Max Planck Institute for the Physics of Complex Systems
- Max Planck Institute of Molecular Cell Biology and Genetics
- National Institute of General Medical Sciences
- National Institutes of Health
- Yale University