Charge shielding effects of PEG bound to NH2-terminated PAMAM dendrimers – an experimental approach
Abstract
An experimental technique to probe intramolecular interactions of PEG–PAMAM conjugates and surface charge presentation. Increasing PEG chain length increases non-covalent shielding, but increasing chain density decreases PEG surface association.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2023
- Source ID
- 10.1039/d2sm01698b
Entities
People
- Alan J. Grodzinsky
- Brandon M. Johnston
- Paula T. Hammond
Organizations
- Congressionally Directed Medical Research Programs
- Koch Institute for Integrative Cancer Research at MIT
- Massachusetts Institute of Technology
- National Institute of Biomedical Imaging and Bioengineering