Passivating quantum dots against histag-displaying enzymes using blocking peptides: salient considerations for self-assembling quantum dot biosensors

Abstract

Peptide-based passivation strategies were developed to prevent the unintended conjugation of his-tagged enzymes to quantum dot (QD) biosensors, enabling the application of QD biosensors in complex assays such as CRISPR-based diagnostics.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 01, 2023
Source ID
10.1039/d3sd00149k

Entities

People

  • Christopher M. Green
  • David A Hastman
  • David A. Stenger
  • Igor L. Medintz
  • Joseph Spangler
  • Kimihiro Susumu
  • Sebastian A Díaz

Organizations

  • American Society for Engineering Education
  • Office of Naval Research
  • United States Naval Research Laboratory

Tags

Readers

  • Molecular Genetics
  • Molecular and Cellular Biochemistry
  • Semiconductor Device Technology

Technology Areas

  • Biotechnology
  • Quantum Computing