Single-nanoparticle detection with slot-mode photonic crystal cavities
Abstract
Optical cavities that are capable for detecting single nanoparticles could lead to great progress in early stage disease diagnostics and the study of biological interactions on the single-molecule level. In particular, photonic crystal (PhC) cavities are excellent platforms for label-free single-nanoparticle detection, owing to their high quality (Q) factors and wavelength-scale modal volumes. Here, we demonstrate the design and fabrication of a high-Q (>104) slot-mode PhC nanobeam cavity, which is able to strongly confine light in the slotted regions. The enhanced light-matter interaction results in an order of magnitude improvement in both refractive index sensitivity (439 nm/RIU) and single-nanoparticle sensitivity compared with conventional dielectric-mode PhC cavities. Detection of single polystyrene nanoparticles with radii of 20 nm and 30 nm is demonstrated in aqueous environments (D2O), without additional laser and temperature stabilization techniques.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jun 29, 2015
- Source ID
- 10.1063/1.4923322
Entities
People
- Cheng Wang
- Marko Loncar
- Qimin Quan
- Shota Kita
- Yihang Li
Organizations
- Air Force Office of Scientific Research
- Harvard University
- Tsinghua University