Efficient extraction of oil from droplet microfluidic emulsions
Abstract
Droplet microfluidic techniques can perform large numbers of single molecule and cell reactions but often require controlled, periodic flow to merge, split, and sort droplets. Here, we describe a simple method to convert aperiodic flows into periodic ones. Using an oil extraction module, we efficiently remove oil from emulsions to readjust the droplet volume fraction, velocity, and packing, producing periodic flows. The extractor acts as a universal adaptor to connect microfluidic modules that do not operate under identical flow conditions, such as droplet generators, incubators, and merger devices.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 01, 2017
- Source ID
- 10.1063/1.4984035
Entities
People
- Adam R. Abate
- David A Weitz
- I. C. Clark
- J. R. Haliburton
- Ralph A Sperling
- Samuel Kim
Organizations
- Defense Advanced Research Projects Agency
- German Research Foundation
- Harvard University
- National Institutes of Health
- National Science Foundation
- University of California