Cortical chimera states predict epileptic seizures
Abstract
A chimera state is a spatiotemporal pattern of broken symmetry, where synchrony (coherent state) and asynchrony (incoherent state) coexist. Here, we report chimera states in electrocorticography recordings preceding, by several hours, each of seven seizures in one patient with epilepsy. Before the seizures, the onset channels are not synchronized, while the remaining channels are synchronized. During the seizures, this pattern of behavior flips and the nononset channels show a more asynchronous behavior. At a seizure offset, synchrony can be observed that might facilitate termination.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 01, 2019
- Source ID
- 10.1063/1.5139654
Entities
People
- Claudia Lainscsek
- Nuttida Rungratsameetaweemana
- Syndey S Cash
- Terrence J. Sejnowski
Organizations
- Harvard Medical School
- National Institute of Biomedical Imaging and Bioengineering
- National Institute of Neurological Disorders and Stroke
- Office of Naval Research
- Salk Institute for Biological Studies
- United States Army Research Laboratory
- University of California, San Diego