Pulsed two-photon coherent control of channelrhodopsin-2 photocurrent in live brain cells
Abstract
Channelrhodopsin-2 (ChR2) is an ion channel activated by the absorption of light. A recent experiment demonstrated that the current emanating from neurons in live brain cells expressing ChR2 can be controlled using two-photon phase control. Here, we propose an experimentally testable coherent control mechanism for this phenomenon. Significantly, we describe how femtosecond, quantum coherent processes arising from weak-field ultrafast excitation are responsible for the reported control of the millisecond classical dynamics of the neuronal current.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 16, 2020
- Source ID
- 10.1063/5.0012642
Entities
People
- Cyrille Lavigne
- Paul Brumer
Organizations
- Air Force Office of Scientific Research
- University of Toronto