Smart nanosystems: Bio-inspired technologies that interact with the host environment
Abstract
Nanoparticle technologies intended for human administration must be designed to interact with, and ideally leverage, a living host environment. Here, we describe smart nanosystems classified in two categories: ( i ) those that sense the host environment and respond and ( ii ) those that first prime the host environment to interact with engineered nanoparticles. Smart nanosystems have the potential to produce personalized diagnostic and therapeutic schema by using the local environment to drive material behavior and ultimately improve human health.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Nov 23, 2015
- Source ID
- 10.1073/pnas.1508522112
Entities
People
- Ester J. Kwon
- Justin H. Lo
- Sangeeta N. Bhatia
Organizations
- Brigham and Women's Hospital
- Harvard Medical School
- Massachusetts Institute of Technology
- National Cancer Institute