Behavioral assessment of sensitivity to intracortical microstimulation of primate somatosensory cortex
Abstract
Electrical stimulation of sensory structures in the brain is a powerful tool to investigate neural circuits and may provide a means to restore sensation for patients for whom stimulation of the nerve is not an option. For both purposes, however, it is critical to understand how the design of the stimulation shapes the evoked sensory experience. With this in mind, we investigate the ability of monkeys to detect and discriminate trains of electrical pulses delivered to their somatosensory cortex through chronically implanted electrode arrays. We show that artificial touch is highly dependent on various features of the electrical stimuli and discuss the implications of our results for the use of electrical stimulation in neuroscience and neural engineering.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 26, 2015
- Source ID
- 10.1073/pnas.1509265112
Entities
People
- Francesco V. Tenore
- Gregg A. Tabot
- Robert A. Gaunt
- Sliman J. Bensmaia
- Sungshin Kim
- Thierri Callier
Organizations
- Defense Advanced Research Projects Agency
- Johns Hopkins University
- University of Chicago
- University of Pittsburgh