Printed droplet microfluidics for on demand dispensing of picoliter droplets and cells
Abstract
Single-cell biology requires the ability to construct experiments with single-cell precision, large numbers, and extremely small fluid volumes. To address this need, we have developed a new technology, printed droplet microfluidics, which encapsulates reagents and single cells in picoliter droplets, then actively selects and deposits desired droplets in an arrayed format on a printing substrate. This technology enables the construction of a large number of relevant single-cellular and multicellular experiments and enables new methods of detection.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 31, 2017
- Source ID
- 10.1073/pnas.1704020114
Entities
People
- Adam R. Abate
- Christian A. Siltanen
- Jesse Q. Zhang
- Payam Shahi
- Russell H. Cole
- Sean Poust
- Shi-yang Tang
- Zev J Gartner
Organizations
- Chan Zuckerberg Biohub
- Office of Extramural Research
- University of California
- University of California, San Francisco