Multimodal gradients across mouse cortex
Abstract
The brain is organized into processing streams, along which incoming sensory information is processed at increasingly abstract and integrative levels. This specialization of function is thought to be underpinned by corresponding changes in the brain’s local circuitry. Here we combine a wide range of measurements across the mouse brain, including the expression of genes, cell densities, and axonal connectivity, to show that the properties of local circuits of the mouse brain vary along putative processing streams in a similar way to the primate brain. This similarity across species points to common mechanisms through which mammalian brains may process information.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 19, 2019
- Source ID
- 10.1073/pnas.1814144116
Entities
People
- Ben D. Fulcher
- John D. Murray
- Valerio Zerbi
- Xiao-Jing Wang
Organizations
- ETH Zurich
- National Health and Medical Research Council
- National Institute of Mental Health
- New York University
- Office of Naval Research
- Simons Foundation
- University of Sydney
- Yale University