Preserved capacity for learning statistical regularities and directing selective attention after hippocampal lesions

Abstract

The hippocampus is important for many kinds of learning and memory. We explored the role of the hippocampus in the learning of statistical regularities. We administered a motion discrimination task where expectation about stimulus regularities, the degree of attention afforded to the relevant stimulus, and the amount of available sensory information were manipulated. Although modestly slower overall, patients with bilateral damage to the hippocampus performed similar to controls, exhibiting a normal tendency to respond faster and more accurately when the motion direction was more probable, when the stimulus was better attended, and when more sensory evidence was present. These findings show that the ability to acquire expectations based on regularities of a sensory environment can be independent of the hippocampus.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 06, 2019
Source ID
10.1073/pnas.1904502116

Entities

People

  • John T. Serences
  • Larry R. Squire
  • Nuttida Rungratsameetaweemana

Organizations

  • James S. McDonnell Foundation
  • National Eye Institute
  • National Institute of Mental Health
  • United States Army Research Laboratory
  • University of California, San Diego

Tags

Fields of Study

  • Biology
  • Psychology

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Neuroscience
  • Theoretical Analysis.