Controlling silk fibroin conformation for dynamic, responsive, multifunctional, micropatterned surfaces
Abstract
Silk polymorphism is used to generate composite materials that can wrinkle reversibly and in complex patterns. This is achieved by leveraging and controlling the ability of structural proteins to change their conformation and their stimulus-responsive behavior to offer a different approach to micro/nanopatterning of dynamic, multifunctional biocompatible interfaces. The results show the ability to reshape protein films on the nano- and microscale on demand and generate functional protein surfaces with tunable topography opening possibilities in programmable biomaterial-based interfaces.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Oct 07, 2019
- Source ID
- 10.1073/pnas.1911563116
Entities
People
- Beom Joon Kim
- Berney Peng
- Fiorenzo G Omenetto
- Meng Li
- Wenyi Li
- Yu Wang
- Yuqi Wang
Organizations
- Office of Naval Research
- Sungkyunkwan University
- Tufts University