Multiple areas of the cerebral cortex influence the stomach
Abstract
Despite the longstanding appreciation that how we move, think, and feel has an impact on stomach function, the areas of the cerebral cortex that are the origin of these influences are largely unknown. Here we identify the cortical areas that influence the rat stomach. Output neurons in the rostral insula are the major cortical source of influence over parasympathetic control of the stomach, whereas output neurons in sensorimotor areas of the cortex are the major source of influence over sympathetic control. Thus, cortical areas involved in action, interoception, and emotion differentially influence stomach function.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 20, 2020
- Source ID
- 10.1073/pnas.2002737117
Entities
People
- David Levinthal
- Peter L. Strick
Organizations
- National Institutes of Health
- United States Army
- University of Pittsburgh
- University of Pittsburgh School of Medicine