Ultrasensitive multispecies spectroscopic breath analysis for real-time health monitoring and diagnostics

Abstract

Determining the identity and concentration of the molecules present in breath is a powerful tool to assess the overall health of a person, analogous to blood testing in clinical medicine, but in a faster and less invasive manner. The presence of a particular molecule (or combination of molecules) can indicate the presence of a certain health condition or infection, facilitating a diagnosis. Monitoring the concentration of the molecules of interest over time can help track the development (or recurrence) of a condition, as well as the effectiveness of the administered treatment. To make breath analysis more accessible and widely adopted, we explore a technique to perform breath analysis with high resolution, wide spectral coverage, high specificity, and high sensitivity.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 01, 2021
Source ID
10.1073/pnas.2105063118

Entities

People

  • Bryan Changala
  • David J. Nesbitt
  • Jun Ye
  • Jutta Toscano
  • Qizhong Liang
  • Ya-chu Chan

Organizations

  • Air Force Office of Scientific Research
  • Harvard–Smithsonian Center for Astrophysics
  • National Science Foundation
  • University of Colorado Boulder

Tags

Readers

  • Distributed Systems and Data Platform Development
  • Molecular Photonics/Laser Physics
  • Oncology