EPHecting cell contact by increasing cortical tension

Abstract

EPH/EPHRIN signaling is crucial to the segregation of cell populations during the morphogenesis of many tissues. In this issue, Kindberg et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202005216) show that EPH activation can drive both heterotypic cell repulsion and homotypic aggregation by triggering increased cortical tension.

Document Details

Document Type
Pub Defense Publication
Publication Date
May 17, 2021
Source ID
10.1083/jcb.202105015

Entities

People

  • Andrea I McClatchey

Organizations

  • Children's Tumor Foundation
  • National Institutes of Health
  • United States Department of Defense

Tags

Fields of Study

  • Biology
  • Mathematics

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Breast cancer cell signaling and growth regulation.
  • Molecular Biology and Genetics