Lymph node metastasis: An immunological burden

Abstract

Lymph node metastasis in breast cancer depends in part on the acquisition of an IFN-dependent, MHC-II+ state that induces regulatory T cell expansion and local immune suppression (Lei et al. 2023. J. Exp. Med.https://doi.org/10.1084/jem.20221847).

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 07, 2023
Source ID
10.1084/jem.20230904

Entities

People

  • Amanda W. Lund

Organizations

  • American Association for Cancer Research
  • Cancer Research Institute
  • National Institutes of Health
  • New York University
  • The Mark Foundation for Cancer Research
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Immunology
  • Oncology
  • Pulsed Power and Plasma Physics.