Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
Abstract
The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 µm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusing imaging in brain tissue, and demonstrates the value of these optimized wavelengths for neurobiological applications.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Apr 25, 2019
- Source ID
- 10.1088/1361-6463/ab16b4
Entities
People
- Christopher J Rowlands
- Dai Fukamura
- Daniel Franke
- Moungi Bawendi
- Oliver T. Bruns
- Peter T. C. So
- Rakesh Jain
Organizations
- Army Research Office
- National Institutes of Health
- National Science Foundation
- United States Department of Defense
- Wellcome Trust