Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules
Abstract
Network-based genome-wide association studies (GWAS) aim to identify functional modules from biological networks that are enriched by top GWAS findings. Although gene functions are relevant to tissue context, most existing methods analyze tissue-free networks without reflecting phenotypic specificity.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jul 20, 2017
- Source ID
- 10.1093/bioinformatics/btx344
Entities
People
- Andrew J. Saykin
- Casey S. Greene
- For The Alzheimer’s Disease Neuroimaging Initiative*
- Jason H. Moore
- Jingwen Yan
- Kefei Liu
- Kwangsik Nho
- Shannon L. Risacher
- Shen Li
- Sungeun Kim
- Xiaohui Yao
Organizations
- Indiana University
- State University of New York at Oswego
- United States Department of Defense
- University of Pennsylvania