Active Targeted Surveillance to Identify Sites of Emergence of Hantavirus

Abstract

Endemic outbreaks of hantaviruses pose a critical public health threat worldwide. Hantaan orthohantavirus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS) in humans. Using comparative genomic analyses of partial and nearly complete sequences of HTNV from humans and rodents, we were able to localize, with limitations, the putative infection locations for HFRS patients. Partial sequences might not reflect precise phylogenetic positions over the whole-genome sequences; finer granularity of rodent sampling reflects more precisely the circulation of strains.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 20, 2019
Source ID
10.1093/cid/ciz234

Entities

People

  • Daesang Lee
  • Dong Hyun Song
  • Geum-young Lee
  • Gustavo Palacios
  • Hayne Park
  • Heung-Chul Kim
  • Jaehun Jung
  • Jeong-ah Kim
  • Jin Sun No
  • Jin-won Song
  • Kkothanahreum Park
  • Michael R. Wiley
  • Patrick S. G. Chain
  • Se Hun Gu
  • Seong Tae Jeong
  • Seung-ho Lee
  • Seungchan Cho
  • Sunhye Park
  • Terry A. Klein
  • Won-Keun Kim
  • Yongjin Yi
  • Yujin Kim

Organizations

  • 65th Medical Brigade
  • Agency for Defense Development
  • Armed Forces Health Surveillance Center
  • Korea University
  • Los Alamos National Laboratory
  • National Research Foundation of Korea

Tags

Fields of Study

  • Biology

Readers

  • Infectious Disease/Epidemiology
  • Molecular Biology and Genetics
  • Virology (or Medical Virology).