Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug

Abstract

Nitroglycerine (NTG) given prior to an ischaemic insult exerts cardioprotective effects. However, whether administration of an acute low dose of NTG in a clinically relevant manner following an ischaemic episode limits infarct size, has not yet been explored.

Document Details

Document Type
Pub Defense Publication
Publication Date
Aug 27, 2018
Source ID
10.1093/cvr/cvy222

Entities

People

  • Andreas Daiber
  • Andreas Papapetropoulos
  • Athanasia Chatzianastasiou
  • Derek J Hausenloy
  • Efstathios K Iliodromitis
  • Ingrid Fleming
  • Ioanna Andreadou
  • Kyriakos E Kypreos
  • Peter Brouckaert
  • Sebastian Steven
  • Sofia-iris Bibli
  • Voahanginirina Randriamboavonjy

Organizations

  • Bodossaki Foundation
  • British Heart Foundation
  • Ernst Schering Foundation
  • European Cooperation in Science and Technology
  • European Society of Cardiology
  • Flanders Institute for Biotechnology
  • German Research Foundation
  • Ghent University
  • Goethe University Frankfurt
  • National Institute for Health and Care Research
  • National and Kapodistrian University of Athens
  • Naval Medical Research Center
  • University College London
  • University Medical Center
  • Yong Loo Lin School of Medicine

Tags

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Strategic Security Studies