Mass-Cytometry-Based Quantification of Global Histone Post-Translational Modifications at Single-Cell Resolution Across Peripheral Immune Cells in IBD
Abstract
Current understanding of histone post-translational modifications [histone modifications] across immune cell types in patients with inflammatory bowel disease [IBD] during remission and flare is limited. The present study aimed to quantify histone modifications at a single-cell resolution in IBD patients during remission and flare and how they differ compared to healthy controls.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 26, 2022
- Source ID
- 10.1093/ecco-jcc/jjac194
Entities
People
- Aida Habtezion
- Alex Kuo
- Ananthakrishnan Ganesan
- Denis Dermadi
- Laurynas Kalesinskas
- Lawrence Bai
- Mai Dvorak
- Michele Donato
- Paul J. Utz
- Peggie Cheung
- Purvesh Khatri
- Samuel J S Rubin
- Sarah E Chang
Organizations
- Gates Foundation
- National Institute of Allergy and Infectious Diseases
- Stanford University
- United States Department of Defense