The Cross-sectional and Longitudinal Associations Between IL-6, IL-10, and TNFα and Cognitive Outcomes in the Mayo Clinic Study of Aging

Abstract

Chronic inflammation has been linked with geriatric-related conditions, including dementia. Inflammatory cytokine levels, including interleukin (IL)-6, IL-10, and tumor necrosis factor (TNF) α, in the blood have been associated with cognitive impairment and decline. However, evidence has been mixed.

Document Details

Document Type
Pub Defense Publication
Publication Date
Sep 25, 2018
Source ID
10.1093/gerona/gly217

Entities

People

  • Alexandra M V Wennberg
  • Clinton E. Hagen
  • David S. Knopman
  • Mary M. Machulda
  • Michelle M. Mielke
  • Ronald C. Petersen

Organizations

  • Mayo Clinic
  • National Institute on Aging
  • National Institutes of Health
  • United States Department of Defense

Tags

Fields of Study

  • Medicine

Readers

  • Aviation Safety and Air Traffic Management
  • Immunology and Pathology
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.