The Cross-sectional and Longitudinal Associations Between IL-6, IL-10, and TNFα and Cognitive Outcomes in the Mayo Clinic Study of Aging
Abstract
Chronic inflammation has been linked with geriatric-related conditions, including dementia. Inflammatory cytokine levels, including interleukin (IL)-6, IL-10, and tumor necrosis factor (TNF) α, in the blood have been associated with cognitive impairment and decline. However, evidence has been mixed.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 25, 2018
- Source ID
- 10.1093/gerona/gly217
Entities
People
- Alexandra M V Wennberg
- Clinton E. Hagen
- David S. Knopman
- Mary M. Machulda
- Michelle M. Mielke
- Ronald C. Petersen
Organizations
- Mayo Clinic
- National Institute on Aging
- National Institutes of Health
- United States Department of Defense