Monocytosis Is a Biomarker of Severity in Inflammatory Bowel Disease: Analysis of a 6-Year Prospective Natural History Registry

Abstract

Inflammatory bowel disease (IBD) is associated with alterations of the innate and adaptive immune systems. Monocytes respond to inflammation and infection, yet the relationship between monocytosis and IBD severity is not fully understood. We aimed to characterize the prevalence of monocytosis in IBD and the association between monocytosis and disease severity and IBD-related health care utilization.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 09, 2021
Source ID
10.1093/ibd/izab031

Entities

People

  • Alyce M. Anderson
  • Arthur Barrie
  • Benjamin Click
  • Claudia Ramos-rivers
  • Cynthia Cherfane
  • David G. Binion
  • Dmitriy Babichenko
  • Elyse Johnston
  • Gong Tang
  • Ioannis E. Koutroubakis
  • Jana G. Hashash
  • Jeffrey Dueker
  • Marc Schwartz
  • Michael Dunn
  • Siobhan Proksell

Organizations

  • Cleveland Clinic
  • Lebanese American University
  • National Center for Advancing Translational Sciences
  • National Institutes of Health
  • United States Army Medical Research and Development Command
  • United States Department of Defense
  • University of Pittsburgh
  • University of Pittsburgh Medical Center
  • Washington University in St. Louis

Tags

Fields of Study

  • Medicine

Readers

  • Agricultural Chemistry/Soil Science
  • Immunology and Pathology
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.