Safety and Immunogenicity of Ad26-Vectored HIV Vaccine With Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-Uninfected Adults: A Phase 1/2a Study

Abstract

Developing a cross-clade, globally effective HIV vaccine remains crucial for eliminating HIV.

Document Details

Document Type
Pub Defense Publication
Publication Date
Nov 09, 2022
Source ID
10.1093/infdis/jiac445

Entities

People

  • Christy Comeaux
  • Colleen F Kelley
  • Dan H. Barouch
  • Daniel J. Stieh
  • David C. Montefiori
  • Dimitri Goedhart
  • Etienne Karita
  • Frank Tomaka
  • Galit Alter
  • Georgia D. Tomaras
  • Guido Ferrari
  • Hanneke Schuitemaker
  • Hong Van Tieu
  • Ian Frank
  • Jack Heptinstall
  • James G. Kublin
  • Jennifer A Johnson
  • Joseph Nkolola
  • Julie A. Ake
  • Julie McElrath
  • Kathryn E. Stephenson
  • Katleen Callewaert
  • Kenneth Mayer
  • Kristen W Cohen
  • Lauren Peter
  • Lawrence Corey
  • Lindsey R. Baden
  • Lorenz Scheppler
  • Magda Sobieszczyk
  • Maria G Pau
  • Matthew H Collins
  • Merlin L Robb
  • Michael Keefer
  • Michael S Seaman
  • Michal Sarnecki
  • Nadine Rouphael
  • Paul A Goepfert
  • Philipp Mann
  • Sheetal Sawant
  • Srilatha Edupuganti
  • Stephen C. De Rosa
  • Stephen R Walsh
  • Steven Nijs
  • Susan Buchbinder
  • The Ascent/hvtn118/hpx2003 Study Team
  • Trevor A Crowell
  • Varun K Phadke
  • Zelda Euler

Organizations

  • Beth Israel Deaconess Medical Center
  • Duke University
  • Emory University
  • Fred Hutchinson Cancer Center
  • Gates Foundation
  • Harvard Medical School
  • Harvard University
  • Henry M. Jackson Foundation for the Advancement of Military Medicine
  • Janssen Pharmaceutica
  • Janssen Vaccines
  • National Institute of Allergy and Infectious Diseases
  • National Institutes of Health
  • United States Department of Defense
  • University of Alabama at Birmingham

Tags

Fields of Study

  • Biology

Readers

  • Immunology
  • Systems Analysis and Design

Technology Areas

  • Biotechnology