Protective Efficacy and Long-Term Immunogenicity in Cynomolgus Macaques by Ebola Virus Glycoprotein Synthetic DNA Vaccines

Abstract

There remains an important need for prophylactic anti-Ebola virus vaccine candidates that elicit long-lasting immune responses and can be delivered to vulnerable populations that are unable to receive live-attenuated or viral vector vaccines.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 10, 2018
Source ID
10.1093/infdis/jiy537

Entities

People

  • Alexander Bello
  • Amelia A Keaton
  • Ami Patel
  • Amir S Khan
  • Daniel H. Park
  • Daniel O Villarreal
  • David B. Weiner
  • Devon J. Shedlock
  • Dinah Amante
  • Emma L Reuschel
  • Gary P. Kobinger
  • Gary Wong
  • Geoff Soule
  • Jean Boyer
  • Jewell Walters
  • Jian Yan
  • Jonathan Audet
  • Kar Muthumani
  • Kate E. Broderick
  • Kaylie N Tran
  • Kevin Tierney
  • Kimberly A Kraynyak
  • Marc-antoine De La Vega
  • Megan C. Wise
  • Niranjan Y. Sardesai
  • Ross Plyler
  • Shane Jones
  • Shihua He
  • Trina Racine
  • Veronica L Scott
  • Xiangguo Qiu

Organizations

  • Defense Advanced Research Projects Agency
  • Inovio Pharmaceuticals
  • Laval University
  • National Microbiology Laboratory
  • University of Manitoba
  • University of Pennsylvania
  • William Carey University
  • Wistar Institute

Tags

Fields of Study

  • Biology

Readers

  • Infectious Disease/Epidemiology
  • Systems Analysis and Design
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology