Clinically undetected polyclonal heteroresistance among Pseudomonas aeruginosa isolated from cystic fibrosis respiratory specimens

Abstract

Pseudomonas aeruginosa infection is the leading cause of death among patients with cystic fibrosis (CF) and a common cause of difficult-to-treat hospital-acquired infections. P. aeruginosa uses several mechanisms to resist different antibiotic classes and an individual CF patient can harbour multiple resistance phenotypes.

Document Details

Document Type
Pub Defense Publication
Publication Date
Oct 13, 2022
Source ID
10.1093/jac/dkac320

Entities

People

  • Andrew E Clark
  • Christine A Pybus
  • Daniel Maxwell
  • David E Greenberg
  • Dhara Desai
  • Jiwoong Kim
  • Laura M Filkins
  • Leona White
  • Marguerite L. Monogue
  • Meredith M Rae
  • Richard J. Medford
  • Xiaowei Zhan

Organizations

  • United States Department of Defense
  • University of Texas Southwestern Medical Center
  • University of Texas at Austin

Tags

Fields of Study

  • Biology
  • Medicine

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Microbial Pathology
  • Oncology