Inferences About Drug Safety in Phase III Trials in Oncology: Examples From Advanced Prostate Cancer

Abstract

Safety is a central consideration when choosing between multiple medications with similar efficacy. We aimed to evaluate whether adverse event (AE) profiles of 3 such drugs in advanced prostate cancer could be distinguished based on published literature.

Document Details

Document Type
Pub Defense Publication
Publication Date
Aug 28, 2020
Source ID
10.1093/jnci/djaa134

Entities

People

  • Chana A. Sacks
  • Gita Thanarajasingam
  • Joshua Z. Drago
  • Konrad H Stopsack
  • Michael J. Morris
  • Mithat Gönen
  • Philip W. Kantoff

Organizations

  • Massachusetts General Hospital
  • Mayo Clinic
  • Memorial Sloan Kettering Cancer Center
  • National Cancer Institute
  • Prostate Cancer Foundation
  • United States Department of Defense
  • Weill Cornell Medicine

Tags

Readers

  • Clinical Trial Research.
  • Molecular and genetic basis of cancer.
  • Trauma or Military Medicine

Technology Areas

  • AI & ML
  • AI & ML - Bayesian Inference