Serum Concentrations of Per- and Polyfluoroalkyl Substances and Risk of Renal Cell Carcinoma
Abstract
Per- and polyfluoroalkyl substances (PFAS) are highly persistent chemicals that have been detected in the serum of over 98% of the US population. Studies among highly exposed individuals suggest an association with perfluorooctanoic acid (PFOA) exposure and kidney cancer. It remains unclear whether PFOA or other PFAS are renal carcinogens or if they influence risk of renal cell carcinoma (RCC) at concentrations observed in the general population.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Sep 18, 2020
- Source ID
- 10.1093/jnci/djaa143
Entities
People
- Antonia M. Calafat
- Catherine L Callahan
- Debra T. Silverman
- Jonathan N Hofmann
- Joseph J Shearer
- Joshua Sampson
- Mark P. Purdue
- Neal D. Freedman
- Rena R Jones
- Venkata S. Sabbisetti
- Wen-Yi Huang
Organizations
- Brigham and Women's Hospital
- Centers for Disease Control and Prevention
- National Cancer Institute
- National Institutes of Health