Effect of the p53 P72R Polymorphism on MutantTP53Allele Selection in Human Cancer
Abstract
TP53 mutations occur in more than 50% of cancers. We sought to determine the effect of the intragenic P72R single nucleotide polymorphism (SNP; rs1042522) on the oncogenic properties of mutant p53.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Feb 08, 2021
- Source ID
- 10.1093/jnci/djab019
Entities
People
- Alan G Raetz
- Anthony N Karnezis
- Cristabelle De Souza
- Dennis Minn
- Dennis Montoya
- Devin C Koestler
- Harikumara Reddy
- Jeremy Chien
- Jill A. Madden
- Kay Minn
- Neeki Tahmassebi
- Nina Nelson
- Wen-wu Xiao
- Zheng Zhu
Organizations
- Boston Children's Hospital
- National Institutes of Health
- Stanford University
- UC Davis Medical Center
- United States Department of Defense
- University of California, Davis
- University of Kansas
- University of Massachusetts
- University of New Mexico