Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy

Abstract

A total of 10%–20% of patients develop long-term toxicity following radiotherapy for prostate cancer. Identification of common genetic variants associated with susceptibility to radiotoxicity might improve risk prediction and inform functional mechanistic studies.

Document Details

Document Type
Pub Defense Publication
Publication Date
May 16, 2019
Source ID
10.1093/jnci/djz075

Entities

People

  • Alison Dunning
  • Ana M. Carballo
  • Ana Vega
  • Andrea Baran
  • Antonio Di Narzo
  • Antonio Gómez-caamaño
  • Barry S. Rosenstein
  • Catharine M. West
  • David P. Dearnaley
  • Derick R. Peterson
  • Emma Hall
  • Gaurav Pandey
  • Gillian C. Barnett
  • Harry Ostrer
  • Hiroshi Tsuji
  • Ke Hao
  • Kim Deruyck
  • Laura Fachal
  • Leila Dorling
  • Matthew Parliament
  • Matthew R Sydes
  • Mehmet Eren Ahsen
  • Michelle Hollenberg
  • Michelle Janelsins
  • Miguel E Aguado-Barrera
  • Nawaid Usmani
  • Neil G. Burnet
  • Nelson N. Stone
  • Paul D P Pharoah
  • Paula Peleteiro
  • Ramón Lobato-Busto
  • Rebecca M Elliott
  • Richard Stock
  • Rosalind Eeles
  • Sandeep Singhal
  • Sarah Kerns
  • Sarah L. Gulliford
  • Shiro Saito
  • Søren M Bentzen
  • Takashi Imai

Organizations

  • Albert Einstein College of Medicine
  • Cancer Research UK
  • Columbia University
  • Ghent University Hospital
  • Icahn School of Medicine at Mount Sinai
  • Institute of Cancer Research
  • National Institutes of Health
  • The Royal Marsden NHS Foundation Trust
  • United States Department of Defense
  • University College London
  • University of Alberta
  • University of Cambridge
  • University of Manchester
  • University of Maryland
  • University of Rochester
  • University of Santiago de Compostela

Tags

Fields of Study

  • Physics

Readers

  • Molecular Genetics
  • Oncology and Biomarker-Based Cancer Detection.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology