Circulating Insulin-Like Growth Factor 1–Related Biomarkers and Risk of Lethal Prostate Cancer
Abstract
Experimental and epidemiologic evidence supports the role of circulating insulin-like growth factor-1 (IGF-1) levels with the risk of prostate cancer. Most circulating IGF-1 is bound to specific binding proteins, and only about 5% circulates in a free form. We explored the relation of free IGF-1 and other components of the IGF system with lethal prostate cancer.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 15, 2021
- Source ID
- 10.1093/jncics/pkab091
Entities
People
- Chaoran Ma
- Kathryn L. Penney
- Kathryn M. Wilson
- Lorelei A. Mucci
- Meir J. Stampfer
- Michael Pollak
- Ye Wang
Organizations
- Harvard Medical School
- Harvard University
- McGill University
- National Institutes of Health
- United States Department of Defense