Novel Real-time Digital Pressure Sensor Reveals Wide Variations in Current Nerve Crush Injury Models
Abstract
Introduction: Peripheral nerve crush injury (PNCI) models are commonly used to study nerve damage and the potential beneficial effects of novel therapeutic strategies. Current models of PNCI rely on inter-device and operator precision to limit the variation with applied pressure. Although the inability to accurately quantify the PNCI pressure may result in reduced reproducibility between animals and studies, there is very limited information on the standardization and quantification of applied pressure with PNCI. To address this deficit, we constructed a novel device comprised of an Arduino UNO microcontroller board and Force Sensitive Resistor capable of reporting the real-time pressure applied to a nerve.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2021
- Source ID
- 10.1093/milmed/usaa346
Entities
People
- Grant D. Wandling
- John C Elfar
- Jung Il Lee
- M. A. Hassan Talukder
- Prem Kumar Govindappa
Organizations
- Hanyang University
- National Institutes of Health
- Pennsylvania State University
- United States Department of Defense