Independent Evaluation of Two Prototype Immunochromatographic Tests for Dengue Fever Developed by InBios

Abstract

Dengue fever, caused by any of the four dengue viruses (DENV1–4), is endemic in more than 100 countries around the world. Each year, up to 400 million people get infected with dengue virus. It is one of the most important arthropod-borne viral diseases. Dengue’s global presence poses a medical threat to deploying military personnel and their dependents. An accurate diagnosis followed by attentive supportive care can improve outcomes in patients with severe dengue disease. Dengue diagnostic tests based on PCR and ELISA platforms have been developed and cleared by the U.S. FDA. However, these diagnostic assays are laborious and usually require highly trained personnel and specialized equipment, which presents a significant challenge when conducting operations in austere and resource-constrained areas. InBios International, Inc. (Seattle, WA) has developed two rapid and instrument-free immunochromatographic test prototype devices (multiplex and traditional formats) for dengue diagnosis.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jan 11, 2021
Source ID
10.1093/milmed/usaa553

Entities

People

  • Calli M Rooney
  • Cheng-rei Lee
  • Damon W Ellison Phd
  • Gabriel N Defang Phd
  • Hua-wei Chen
  • Marshall Van De Wyngaerde
  • Maya Williams Phd
  • Shuenn-jue L. Wu
  • Tania D Maldonado

Organizations

  • Naval Medical Research Center
  • Walter Reed Army Institute of Research

Tags

Readers

  • Infectious Disease/Epidemiology
  • Systems Analysis and Design
  • Virology (or Medical Virology).