Real-Time Measurements of Oral Mucosal Carbon Dioxide (POMCO2) Reveals an Inverse Correlation With Blood Pressure in a Porcine Model of Coagulopathic Junctional Hemorrhage
Abstract
Shock states that occur during, for example, profound hemorrhage can cause global tissue hypoperfusion leading to organ failure. There is an unmet need for a reliable marker of tissue perfusion during hemorrhage that can be followed longitudinally. Herein, we investigated whether longitudinal POMCO2 tracks changes in hemodynamics in a swine model of coagulopathic uncontrolled junctional hemorrhage.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 26, 2023
- Source ID
- 10.1093/milmed/usad336
Entities
People
- Biebele Abel
- Brandon Propper
- David M Burmeister
- Irvin Pierskalla
- Jim Hays
- John A. Mares
- Joseph M. White
- Justin Hutzler
- Kimberly A Gerling
Organizations
- Defense Health Agency
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- Johns Hopkins School of Medicine
- Uniformed Services University of the Health Sciences
- United States Army Medical Research and Development Command
- Walter Reed National Military Medical Center