Autoimmunity-Associated Gut Commensals Modulate Gut Permeability and Immunity in Humanized Mice

Abstract

Although the etiology of rheumatoid arthritis (RA) is unknown, recent studies have led to the concept that gut dysbiosis may be involved in onset. In this study, we aimed to determine if human gut commensals modulate the immune response and gut epithelial integrity in DQ8 mice.

Document Details

Document Type
Pub Defense Publication
Publication Date
Mar 01, 2019
Source ID
10.1093/milmed/usy309

Entities

People

  • Baskar Balakrishnan
  • David Luckey
  • Veena Taneja

Organizations

  • Mayo Clinic
  • United States Department of Defense

Tags

Fields of Study

  • Biology
  • Medicine

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Immunology