Temporal Effects of 2% Pilocarpine Ophthalmic Solution on Human Pupil Size and Accommodation
Abstract
First responders and those who work with organophosphate (OP) compounds can experience ocular symptoms similar to those caused by exposure to low levels of nerve agents. This study was designed to examine the efficacy of a safe, clinically available, simulant that reproduces ocular symptoms associated with low-level OP exposure. Among these ocular symptoms are a constriction of the pupils (miosis), decreased visual acuity, and changes in accommodation.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Jan 01, 2020
- Source ID
- 10.1093/milmed/usz235
Entities
People
- Andrew D. Johnson
- Mary B Mccann
- Micah Kinney Lcdr
- Michael Reddix
Organizations
- Defense Threat Reduction Agency
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- Naval Medical Research Unit Dayton