Direct Peritoneal Resuscitation Improves Survival in a Murine Model of Combined Hemorrhage and Burn Injury

Abstract

Combined burn injury and hemorrhagic shock are a common cause of injury in wounded warfighters. Current protocols for resuscitation for isolated burn injury and isolated hemorrhagic shock are well defined, but the optimal strategy for combined injury is not fully established. Direct peritoneal resuscitation (DPR) has been shown to improve survival in rats after hemorrhagic shock, but its role in a combined burn/hemorrhage injury is unknown. We hypothesized that DPR would improve survival in mice subjected to combined burn injury and hemorrhage.

Document Details

Document Type
Pub Defense Publication
Publication Date
Jul 07, 2020
Source ID
10.1093/milmed/usz430

Entities

People

  • Alex B. Lentsch
  • Andrew D. Jung
  • Brian Gavitt
  • Charles C. Caldwell
  • Lou Ann Friend
  • Rebecca Schuster
  • Sabre Stevens-topie
  • Timothy A. Pritts

Organizations

  • United States Air Force
  • University of Cincinnati

Tags

Fields of Study

  • Medicine

Readers

  • Trauma Surgery or Emergency Medicine.