Conditional reprogramming culture conditions facilitate growth of lower-grade glioma models
Abstract
The conditional reprogramming cell culture method was developed to facilitate growth of senescence-prone normal and neoplastic epithelial cells, and involves co-culture with irradiated fibroblasts and the addition of a small molecule Rho kinase (ROCK) inhibitor. The aim of this study was to determine whether this approach would facilitate the culture of compact low-grade gliomas.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Dec 01, 2020
- Source ID
- 10.1093/neuonc/noaa263
Entities
People
- Alan Cohen
- Charles G. Eberhart
- David White
- Eli Bar
- Eric M. Jackson
- Eric Raabe
- Fausto J Rodriguez
- Jeff Mumm
- Jeffrey Rubens
- Jennifer Bynum
- Liam Chen
- Linda Resar
- Liqun Jiang
- Mari Groves
- Ming Yuan
Organizations
- Alex's Lemonade Stand Foundation
- Johns Hopkins University
- United States Department of Defense
- University of Maryland