Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population
Abstract
Pathogen-based diagnostics for acute respiratory infection (ARI) have limited ability to detect etiology of illness. We previously showed that peripheral blood-based host gene expression classifiers accurately identify bacterial and viral ARI in cohorts of European and African descent. We determined classifier performance in a South Asian cohort.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- May 26, 2020
- Source ID
- 10.1093/ofid/ofaa194
Entities
People
- Ajith Nagahawatte
- Bradly P. Nicholson
- Champica K. Bodinayake
- Christopher W Woods
- Elizabeth A. Petzold
- Emily R. Ko
- Ephraim L Tsalik
- Geoffrey S Ginsburg
- L Gayani Tillekeratne
- Megan E. Reller
- Micah T McClain
- Ricardo Henao
- Ruvini Kurukulasooriya
- Sunil Suchindran
- Thomas W. Burke
- Vasantha Devasiri
Organizations
- Duke Global Health Institute, Duke University
- Duke University
- Duke–NUS Medical School
- Durham Regional Hospital
- Institute for Medical Research
- National Institute of Allergy and Infectious Diseases
- Office of Naval Research
- United States Army Medical Research and Development Command
- University of Ruhuna