Inflammatory Biomarkers Do Not Differ Between Persistently Seronegative vs Seropositive People With HIV After Treatment in Early Acute HIV Infection
Abstract
Persistent viral activity may cause enduring seropositivity and inflammation in treated people with HIV (PWH). We compared inflammatory biomarkers between early treated PWH who remained seronegative or seroconverted and found similar levels of D-dimer, soluble cluster of differentiation 14, C-reactive protein, and interleukin-6, indicating that seronegativity does not affect chronic inflammation in early treated PWH.
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 26, 2020
- Source ID
- 10.1093/ofid/ofaa383
Entities
People
- Adam Rupert
- Catherine W Cai
- Donn J. Colby
- Eugène Kroon
- Helene C Highbarger
- Irini Sereti
- Jintanat Ananworanich
- Mark de Souza
- Perrine Lallemand
- Robin Dewar
- Sandhya Vasan
- Sasiwimol Ubolyam
- Supanit Pattanachaiwit
- Suteeraporn Pinyakorn
- Tippawan Pankam
Organizations
- Henry M. Jackson Foundation for the Advancement of Military Medicine
- National Cancer Institute
- National Institute of Allergy and Infectious Diseases
- National Institutes of Health
- Thai Red Cross Society
- U.S. Military HIV Research Program
- United States Army Medical Research and Development Command
- Walter Reed Army Institute of Research