Powassan Virus Neuropathology and Genomic Diversity in Patients With Fatal Encephalitis
Abstract
Powassan virus (POWV) is an emerging cause of severe encephalitis; very little is known about human pathogenicity due to challenges in diagnosis and viral RNA recovery. We present 3 patients with fatal encephalitis due to POWV lineage II (deer tick virus).
Document Details
- Document Type
- Pub Defense Publication
- Publication Date
- Aug 29, 2020
- Source ID
- 10.1093/ofid/ofaa392
Entities
People
- Anne Piantadosi
- Catherine A Freije
- Christopher Tomkins-tinch
- Daniel S. Park
- Erica Normandin
- Isaac H Solomon
- Jacob Lemieux
- Pardis C. Sabeti
- Shibani S. Mukerji
- Siavash Zamirpour
Organizations
- Brigham and Women's Hospital
- Broad Institute
- Defense Advanced Research Projects Agency
- Emory University
- Harvard College
- Harvard Medical School
- Harvard T.H. Chan School of Public Health
- Harvard University
- Howard Hughes Medical Institute
- Massachusetts General Hospital
- National Institutes of Health